Tangential flow filtration (TFF) requires precise control of the recirculation flow rate, chromatography demands a steady feed, and shear-sensitive biologics necessitate gentle handling. Faced with multiple demands from flow rate, pressure, and shear force, how do you choose a pump suitable for the process? From process development to large-scale production, pump selection should not only pay attention to conveying performance, but also comprehensively consider liquid receiving materials, cleaning verification, batch switching, system integration and daily maintenance.

QUATTROFLOW®The four-plunger diaphragm pump achieves gentle delivery akin to a rhythmic “heartbeat” through interconnected diaphragm strokes. Its design eliminates the need for a mechanical seal, and the wetted parts have no rotating components, helping to reduce particles generated by wear. Low pulsation and a wide flow‑rate adjustment range can meet the requirements of processes such as filtration and chromatography for steady flow and low‑shear pumping.

QUATTROFLOW for different production needs®Offers both reusable (MU) and single-use (SU) pumps. MU pumps feature stainless steel pump chambers and support clean-in-place (CIP) and steam-in-place (SIP); SU pumps use fully replaceable plastic wetted pump chambers, reducing chamber cleaning and associated cleaning validation efforts and facilitating batch changes in multi-product manufacturing. In addition, QUATTROFLOW®Skid-mounted pumps integrate the pump chamber, drive ring, motor, and pump housing into a single unit, and are available with either three-phase induction motors or servo motors to meet the integration requirements of various systems.

On December 1, 2026 (Tuesday), bushiji pump (Tianjin) Co., Ltd. will be a guest in rongge live studio, bringing an online seminar on the application of four plunger diaphragm pump in the biopharmaceutical industry.

This seminar was presented by Richard Luo, Product Manager at PSG. He is responsible for QUATTROFLOW®, Wilden®And HydroTM product management and technical support in the Chinese market, familiar with biopharmaceutical and sanitary process requirements.

Starting from the working principle and technical characteristics of four plunger diaphragm pump, the seminar will introduce MU/SU series, skid pump and product update, and combine compliance and certification requirements, verification data and typical applications, share Key selection points and daily operation and maintenance knowledge.

No matter you are evaluating the bio-pharmaceutical fluid delivery plan or engaged in research and development, process, equipment, procurement or system integration, you are welcome to sign up for the meeting, discuss with us how to make the pump selection better match the process requirements.

Sign up now to learn about QUATTROFLOW®Technical features and application practice of four plunger diaphragm pump!