In the PDRN track, fish source, plant source and recombination source appear one after another, and molecular weight, sequence characteristics, methylated state and efficacy mechanism are all put under the magnifying glass. The form of raw materials has also begun to affect product development. The aqueous solution is suitable for Essence, toner and lotion, cream and facial mask. The oil-soluble form can enter essence oil, ointment and makeup. Pure powder allows the formulator to add it flexibly according to the dosage form and target concentration. Making PDRN into pure powder seems to be just a form change, which involves extraction and purification, activity maintenance, batch control and system compatibility. The concept of ingredients can be copied quickly. How to make DNA fragments enter more products stably is the real examination question faced by the industrialization of raw materials.

Yu Su PDRN is taken from spirulina in zabye Salt Lake, Tibet. The research and development team of Hemei biology established a DNA sequence library by high-throughput sequencing, and selected 601 natural DNA fragments that do not coincide with the human genome and contain CpG motif, with the help of AI computational biology, molecular docking and cell experiments, the immune regulation pathways of hypomethylated DNA and TLR9-DC-Treg are studied. The sequence research at the front end is also extended to the raw material form. Yu Su launched water-soluble pure powder SD, as well as OR products oriented to plant source concepts and oral care applications, providing more choices for different formulation systems such as skin care, scalp and makeup. Spirulina source PDRN raw materials have completed the registration of medical device master documents. According to the experimental data provided by Hemei biology, 0.125% of the callus PDRN increases FLG gene expression by 54.44% and cell scratch healing rate by 36.42% in related skin cell experiments; OR products also show the potential of inflammation inhibition and barrier repair in oral cell models.

From 14:00 to 15:00 on August 18, 2026 (Tuesday), Dr. Li Junxiang, chief technology officer of Hemei biology and deputy director of aging Science Innovation Research and Development Center of Tsinghua Yangtze River Delta Research Institute, will be a guest in rongge live broadcast room, we will share the sequence screening of spirulina PDRN, the study of hypomethylated DNA immune repair, pure powder technology and efficacy verification, and analyze the application directions of skin care, scalp and oral care. This seminar is open to brand owners, OEM/ODM enterprises, and recipe, research and development and product developers.

PDRN has entered the stage of refined development. Which source and form should be selected for the next product, and how to establish differentiation evidence? Welcome to the live room and disassemble the answer together!